Serenopathic drugs of natural origin may satisfy cumulative totality impact assessment.  There are apparent drugs that help in our world with pain.  However, it has been difficult to do a cumulative totality impact assessment to understand it.  It confuses me sometimes because God gave us our natural resources, environment, and minds to determine what to use in nature.  These are so-called licit drugs that are derived initially from nature but may go through synthetic processing that may not be healthy for us.  What comes to mind as far as illicit drugs are concerned is marijuana. I know it has been approved for use in most states, but the federal government is still against it.  The other thing that comes to mind is natural mushrooms and their use as food, teas, etc.  It leaves people very confused as to what to do.  We need a cumulative totality impact assessment to determine the cumulative totality of health potential on both the person and broader levels up to society.  With the We Me Earth Unidiversity Earth Research Explorers Cycle, everyone contributes to understanding things like this. Since everyone is involved, everyone goes through their own experiences and can shed light on everything that contributes to a cumulative totality impact assessment.  Therefore, this cycle contributes to finding knowledge that is close to reality about whether to do something or not.  It is my philosophy that those drugs that are closer to nature may be healthier for you.  However, the pharmaceutical industry produces drugs that are highly manufactured and altered, making them unnatural, which leads me to believe that they could be contributing to cancer.  The healthiest natural drugs are natural endorphins produced when involved with strength, fitness, and conditioning.  Hence, strength, fitness, and conditioning are the most holistic way forward.  However, when it’s not an option, serenopathic drugs of natural origin may be a solution to our problems